Traces of Leonardo da Vinci's DNA May Have Been Discovered on a Red Chalk Drawing Called 'Holy Child'
Synthesis4 Sources
January 6, 2026

Traces of Leonardo da Vinci's DNA May Have Been Discovered on a Red Chalk Drawing Called 'Holy Child'

Quick Overview

Scientists have potentially identified traces of Leonardo da Vinci's DNA on a red chalk drawing titled "Holy Child," marking a significant step in "arteomics," though definitive proof remains elusive.

  • DNA Source: Y-chromosome sequences were recovered from the "Holy Child" drawing and a letter from a da Vinci cousin.
  • Genetic Link: The DNA belongs to a genetic group with common ancestors in Tuscany, Leonardo's birthplace.
  • Authorship Debate: The "Holy Child" drawing's authorship is disputed, with stylistic elements like left-handed hatching suggesting da Vinci, but some attribute it to his students.
  • Challenges: No direct DNA reference from Leonardo exists, as his burial site was disturbed and he had no direct descendants, complicating definitive identification.
  • Future Research: The Leonardo da Vinci DNA Project (LDVP) aims to compare these samples with DNA from recently identified living descendants of his father and relatives' tombs.
  • Arteomics: This research showcases arteomics as an emerging field for authenticating art, potentially supplementing traditional connoisseurship with biological evidence.

Key Points

Initial DNA Discovery & Linkage

  • Scientists from the Leonardo da Vinci DNA Project (LDVP) report the recovery of Y chromosome DNA sequences from the red chalk drawing 'Holy Child' and a letter penned by Leonardo's cousin. (Source 1, 2, 4)
  • These sequences belong to a genetic grouping of people sharing a common ancestor in Tuscany, Leonardo's birthplace in 1452. (Source 1, 3, 4)
  • The findings, published as a bioRxiv preprint, suggest the DNA on the artwork *could* be Leonardo's, though definitive, unequivocal proof is complex and not yet established. (Source 1, 2, 3)
  • The 'Holy Child' drawing, depicting a young boy, has disputed authorship; stylistic features like left-handed hatching hint at Leonardo, but some experts suggest a student may have created it. (Source 1, 2, 3)

Scientific Methodology & Verification Hurdles

  • DNA was meticulously collected in April 2024 by microbial geneticist Norberto Gonzalez-Juarbe, using swabs on the 'Holy Child' drawing. (Source 1, 3)
  • To minimize contamination, DNA collection from the artwork was exclusively performed by female scientists. (Source 2)
  • The study included various controls, such as drawings by other artists, environmental surfaces, and commercially acquired art from the same period. (Source 2)
  • Establishing "unequivocal identity" is "extremely complex" due to the lack of verified DNA samples from Leonardo himself, whose burial site was disturbed, and who had no known direct descendants. (Source 1, 2)
  • Future verification involves comparing samples against Y chromosome DNA from recently identified living descendants of Leonardo's father and DNA from tombs of his relatives. (Source 1, 2, 3)

'Arteomics' and Broader Implications

  • This research is a high-profile proving ground for 'arteomics,' an emerging field that uses biological traces to transform art authentication and preservation. (Source 1, 2)
  • Experts note that DNA and other biological traces could soon supplement traditional connoisseurship, which currently hinges on stylistic analysis and expert opinion. (Source 1)
  • The findings could help resolve authorship disputes for pieces like 'Holy Child' and potentially reveal biological traits, such as exceptional visual acuity, that underpinned Leonardo's genius. (Source 1)
  • The LDVP hopes these results will encourage guardians of Leonardo's works to permit further sampling, as he was known to use his fingers in painting, potentially leaving epidermal cells mixed with colors. (Source 1)

Outline

Discovery of Potential Leonardo da Vinci DNA on 'Holy Child' Drawing

Initial Sampling of 'Holy Child' Drawing

Description and Authorship Dispute of 'Holy Child'

Publication of Findings and Initial DNA Analysis

Complexity of Establishing Unequivocal Identity

Complementary Research for DNA Verification

Methodology and Broader Implications of Arteomics

Praise for the Research Approach

Arteomics as a New Field for Art Authentication

Impact on Art Authentication and Future Sampling

Potential for Understanding Leonardo's Genius

Strategic DNA Collection to Prevent Contamination

Broader Context and Further Evidence

Comparative Analysis with Other Artifacts and Controls

Discovery of Diverse Biological Traces

Specific Non-Human DNA Findings

Evidence of Rodent-Rich Environments

Identification of Leonardo's Living Descendants

AI saves you up to 40 minutes

Similar Articles